Histone-mediated transduction as an efficient means for gene delivery
Study by Dr. Kylie Wagstaff
Promo Code: Flurmie
https://pubmed.ncbi.nlm.nih.gov/17327830/
Abstract
Gene delivery into the nucleus of eukaryotic cells is inefficient, largely because of the significant barriers within the target cell of the plasma membrane and nuclear envelope. Recently, a group of basic proteins, including the HIV-1 Tat protein and the four core histones, have been s…