Early Treatment Studies to "prevent hospitalization" are doomed when "80-85% of cases are mild or asymptomatic" to begin with
You have to isolate the 15% who are SICK and then "treat" or test on them and them ONLY. But by then, it's "too late" says Kory. Think how bad it would have been if they had not taken the Mectin
It is entirely possible that I am missing something and welcome being corrected by Flurm or other Numbers Folks.
When your primary outcome is…DIDN’T GET HOSPITALIZED with the syndrome and your syndrome has an 80- 85% YOU WON’T GET SICK ANYWAY built in failsafe, how will you show what is making people sick or making them not get sick?
Unless you remove that group from your treatment test?
I *think* this is the Argentina Study which Bret Weinstein pushed on How to Save the World and Pierre Kory pushed like a huckster at Congress Alternative Treatments hearing before doing the TV interview.
*edit to add, maybe this one?
https://www.medrxiv.org/content/10.1101/2020.09.10.20191619v1.full
The remainder of this post will be unpacking another study on IVM via…Argentina.
Kory is regurgitating the “I’m a lung and ICU doctor” and know my shit routine that he used in Ron Johnson Sell the War on the Virus hearing in May, 2020.
Alright.
I actually intend to not dive into the Soap Opera of Pierre Kory and Bret Weinstein, which people do respond to, either favorably or wanting to eat my liver.
I want to actually try to unpack a giant logical flaw with “early treatment” studies which purport to show that a modality, say Ivermectin or a glass of water and a hamburger reduce the risk of being hospitalized.
Here is the Argentina study. Link to study and download of supplementary materials.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683865/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683865/bin/13063_2020_4813_MOESM1_ESM.pdf
Let’s go through this and isolate some shitfuckery.
Inclusion Criteria: PCR Test diagnosed. 👇
PCR Test diagnosis is unreliable due to false positives and amplifying sequences that can find anything in anybody, said Kary Mullis, PCR inventor.
And further finding sequences that have not been isolated directly from diagnosed hosts and then proven repeatedly to make others ill…but rather plopped into cell cultures of monkey kidney cells with additional DNA (fetal calf serum) added and antibiotics then checking back later and saying, “See! We found it!”
“Confirmed diagnosis of COVID-19 by polymerase chain reaction (not a) test for detection of SARS-Cov2 in the last 48-hours.”
Okay, for the sake of discussion, say you actually did find the virus that dwells within the public, this alleged novel super-killer.
Let’s go to the supplementary materials introduction.
“80-85% of cases is mild or asymptomatic”
It is a pathology that in approximately 80-85% of cases is mild or asymptomatic and around 15% of patients will have more severe forms. The latter are life-threatening and this makes it necessary to have a specific treatment3.
This is the shitfuckery of early treatment to reduce hospitalization study.
You cannot prove that Ivermectin or any drug or modality is going to prevent hospitalization when 80-85% were never going to the hospital to begin with.
You cannot prove that Ivermectin or any drug or modality is going to prevent hospitalization when 80-85% were never going to the hospital to begin with.
You cannot prove that Ivermectin or any drug or modality is going to prevent hospitalization when 80-85% were never going to the hospital to begin with.
“Think how bad it would have been if they had not taken the shots Ivermectin…”
So boiled down:
We wish to study the effects of a drug on this disease diagnosed with an inaccurate, unreliable test and even if it is accurate, 80-85% are mild or aysmptomatic.
Now, based on that 15% of maybe accurately diagnosed that do get sick, you might have a study cohort that you could test the treatment or modality on…you could theoretically show an effect of said modality.
But you will never know until they get sick.
Because that cohort is sick. They are “symptomatic”. They drew the short straw. That tiny fraction of people who “get Covid” who are sick.
But if you toss that big moshy mass of 85% mild or asymptomatic into the trials, well now you have a problem with numerators and denominators.
15/15
15/100
Sure. Okay. 👍
Primary Outcomes: % of hospitalizations in patients with COVID-19.
This binary variable was chosen because the hypothesis is that ivermectin acting in the early stage of the disease could decrease the viral load and improve the host's immune response, thus improving the patient's evolution.
Q: If 85% are asymptomatic with the “disease”, then how can you control who is getting sick or “sicker” with early treatment anything?
What are you treating? 85% are not sick. They are not morbid. They have a mild cold, or nothing.
You have to isolate the 15% who are SICK and then treat them, or test on them and them only.
But by then “it’s too late”, they are already sick.
Did I miss something, STEMS?
This looks to be a similar type thing that the NEJM Pfizer studies did as well before you even get to the selection criteria fraud and un-blinding and relative risk vs. absolute risk shitfuckery.
But me no Math Boy and so I won’t ponder that too much right here as head is already trying to wrap my mind around this “early treatment” for a disease of which 8/10 people are not going to the hospital anyway.
You can “prove” that a hamburger and glass of cold water also “keeps people out of the hospital” BUT ONLY IF YOU EAT IT BEFORE SYMPTOMS GET BAD BECAUSE BY THEN IT’S TOO LATE.
That 85% of asymptomatic has to be removed as you wish to test the treatment on the sick people.
But if they are sick, it’s already too late.
Should have taken the Mectin sooner.
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https://www.buymeacoffee.com/sagehanaJ
related:
The problem Sage is you’re trying to apply logic to the STEM domain. As my wife likes to point out, us STEMs can make whatever justification for whatever outcome we want sound like a good idea.
You WILL take the mectin and like it. For grandma. And just to be sure we got some siMNRA for her. Double plus good citizen. Oh and since you were so good here’s a free coupon for a McDonald’s cricket burger on a cricket meal bun. GMO tomatoes and lettuce included. Sorry no chicken nuggets cause we killed all of them because pcr. Damn. Too late. Going to have to lockdown and take this stuff we just happen to have on the shelf because we so smart and you guys will keep falling for it again. And again. Don’t worry. It’s not a vaccine. It’s a prophylactic. Se we knew you’re too stupid to make the connection. Oh and we forgot. Here’s a free cancer and heart screening. Don’t forget to ask your doctor for the pharma discount coupon when you leave for your favorite drug dispenser. Tell your friends.
Personally, I didn't trust any of what we were told in 2020 or 2021. And when I ended up in the ER in 2021 they wouldn't treat me until I "took the test" which I knew was worthless. It turned out negative, which actually meant nothing, but they treated me and I survived. But ONLY because I refused to be HOSPITALIZED. That fucking ER doctor insisted I should be transferred to another city hospital. I knew if I allowed that I would never come home.
So I had to sign a waiver to get released. I made it home. Fuck them. It's ALL fucking bull shit.