"Johns Hopkins Develops Tiny Machines That Deliver Medicine to the Intestines"
Inspired by a parasitic worm that digs its sharp teeth into its host’s intestines, Johns Hopkins researchers have designed tiny, star-shaped microdevices that can latch onto intestinal mucosa and rele
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Chapter One: Theragripper Machines for the Intestines
I can’t help but read the following press blurb with a dark komedy slant.
Assume that the Owners of the World who fund these studies would like fewer critters to manage.
And better surveillance of the ones who just refuse to cooperate and die.
👇
By Patrick Smith on 02/15/2021
PUBLISHED IN INSIDE TRACT - WINTER 2021
Inspired by a parasitic worm that digs its sharp teeth into its host’s intestines, Johns Hopkins researchers have designed tiny, star-shaped microdevices that can latch onto intestinal mucosa and release drugs into the body.
David Gracias, a professor in the Johns Hopkins University Whiting School of Engineering, and gastroenterologist Florin Selaru, director of the Johns Hopkins Inflammatory Bowel Disease Center, led a team of researchers and biomedical engineers that designed and tested shape-changing machines that mimic the way the parasitic hookworm affixes itself to an organism’s intestines.
Made of metal and thin, shape-changing film and coated in a heat-sensitive paraffin wax, “theragrippers,” each roughly the size of a dust speck, potentially can carry any drug and release it gradually into the body.
The team published results of an animal study in October as the cover article in the journal Science Advances.
Selaru says that extended-release drugs often make their way entirely through the gastrointestinal tract before they’ve finished dispensing their medication.
“Normal constriction and relaxation of GI tract muscles make it impossible for extended-release drugs to stay in the intestine long enough for the patient to receive the full dose,” says Selaru, who has collaborated with Gracias for more than 10 years. “We’ve been working to solve this problem by designing these small drug carriers that can autonomously latch onto the intestinal mucosa and keep the drug load inside the GI tract for a desired duration of time.”
Thousands of theragrippers can be endoscopically deployed in the GI tract. Once released, the machines migrate to the mucosal wall. When the grippers’ wax coating reaches the temperature inside the body, the devices close autonomously and clamp onto the colonic lining. The closing action causes the tiny, six-pointed devices to dig into the mucosa and remain attached to the colon, where they release their medicine payloads gradually into the body. Within a day or two, the theragrippers lose their hold on the tissue and are cleared from the intestine via normal gastrointestinal muscular function.
Of course they do.
Of course the autonomous critters release their grip.
I DON’T WANT AUTONOMOUS MACHINE CRITTERS IN MY INTESTINES.
HOW CAN YOU TRUST THEM TO RELEASE THEIR GRIP? DO THEY SIGN A CONTRACT? IS IT BINDING?
IS THERE AN AUTONOMOUS CRITTER TIME CLOCK?
“We have seen the introduction of dynamic, microfabricated smart devices that can be controlled by electrical or chemical signals”
“We have seen the introduction of dynamic, microfabricated smart devices that can be controlled by electrical or chemical signals,” Gracias says. “But these grippers are so small that batteries, antennas and other components will not fit on them.”
Theragrippers, he says, don’t rely on electricity, wireless signals or external controls. “Instead, they operate like small, compressed springs with a temperature-triggered coating that releases the stored energy autonomously at body temperature.”
The Johns Hopkins researchers fabricated the devices with about 6,000 theragrippers per 3-inch silicon wafer. In their animal experiments, they loaded a pain-relieving drug onto the grippers. The researchers’ studies found that the animals into which theragrippers were administered had higher concentrates of the pain reliever in their bloodstreams than did the control group. The drug stayed in the test subjects’ systems for nearly 12 hours versus two hours in the control group.
Chapter Two: Hacking Humans
The focus of much medical research appears to be how to bypass your body’s protective mechanisms and keep external agents in your body longer.
External agents can be termed medicine or poison, and that distinction can be dependent on dose alone.
As long as it takes…to heal you…or harm you.
Researchers are preoccupied with activating the bypasses of your body’s protective mechanisms in a variety of ways, most notably SMART technology.
Oh, and they would also dearly love to figure out ways to cross the blood-brain barrier.
It is my guiding premise that Modern Day Medicine and the funded Science, errr “science” that fuels it is Depopulation Shitfuckery.
Modern Medicine is a Murder Factory with nicely trimmed lawns.
With falsified science, models, and ostensible reasons of hopey-changey and real depressing reasons of killy-willy.
The Funders would very much like to use SMART Technology to aid and abet their healing-murdering ways.
You do have to install confidence.
Confidence is necessary for a con.
You do have to do some “good”.
This is what melts zeee minds.
☝️Peter Mac (“future may be brighter”) and Jessica Rose and Tess Better Way’s pal, Halma, saying the quiet part out loud.
Bret Weinstein saying the quiet part out loud about gene editing mRNA “technology” deploying pro-grade doublespeak: “elegant technology”…which just elegantly murdered the world for a bullshit staged “emergency” pandemic.
Back to Johns Hopkins study.
Scorpion Translation:
Using the MACHINE “Theragrippers”, we can keep MEDICAL AGENTS in your body longer.
TO HELP YOU.
MULTI DRUG RESISTANCE is their medical ostensible reason to get shit that they give you to “help” you to hang around in the body and complete the healing.
That is the more circumspect portion of the post.
Now let’s lose our minds, shall we?
Chapter Three: Losing our my minds over the Mectin
I kept asking myself why it was Cancer Researchers who had pushed out a “Covid virus isolation” and immediately a study that showed that the Magic Merck Sauce *Ivermectin* allegedly eliminated it in cell culture, (which is fuckery), within 48-hours.
Before the Staged Pandemic was even given permission to pandemic, we knew IVERMECTIN GOOD.
The stage was thus set for a pro wrestling FDA You Are Not a Horse, the Good Covidian People get the mRNA and the Bad Trumpers and Skeptics go get IVM. 👍
(Meanwhile Trump: “I recommend you get the vaccine!” Nothing matters. Nothing matters.)
The timing of that IVM study is incredibly suspect.
By April 3, 2020, we knew! We knew!
The IVM Good eliminate the computer sequence generated “virus” was out SO DANGED FAST from the Cancer Researchers.
Who also study:
Histone-mediated transduction as an efficient means for gene delivery
Gene delivery.
Can you say that again in my good ear?
How convenient for the gene editing Cancer Researchers to “discover” that their Wonder Drug Ivermectin also works on the new fake virus.
Exactly as the new fake virus peak pandemick-ed! *In one New York City.
What timing!
And oh look! Malone was looking for antiviral “vaccines” in 2017.
And so were Kirsch and Evergreen Boy in 2021. Thank goodness we had that Ivermectin study in the books!
“I REPEAT…IF YOU ARE TAKING IVERMECTIN…YOU WILL NOT CONTRACT COVID-19.”
(:20 video)
Chapter Four: Falsified Science
FALSIFIED SCIENTIFIC RESEARCH
Somewhere in this connection, then, was the statement admitting that some scientific research data could be - and indeed has been - falsified in order to bring about desired results. And here was said, "People don't ask the right questions. Some people are too trusting."
Now this was an interesting statement because the speaker and the audience all being doctors of medicine and supposedly very objectively, dispassionately scientific and science being the be all and end-all ... well to falsify scientific research data in that setting is like blasphemy in the church ... you just don't do that.
Anyhow, out of all of this was to come the New International Governing Body, probably to come through the U.N . and with a World Court, but not necessarily through those structures. It could be brought about in other ways. Acceptance of the U.N . at that time was seen as not being as wide as was hoped. Efforts would continue to give the United Nations increasing importance. People would be more and more used to the idea of relinquishing some national sovereignty.
SURVEILLANCE, IMPLANTS, AND TELEVISIONS THAT WATCH YOU
So the next step would be the single card and then the next step would be to replace the single card with a skin implant. The single card could be lost or stolen, give rise to problems; could be exchanged with somebody else to confuse identify. The skin implant on the other hand would be not losable or counterfeitable or transferrable to another person so you and your accounts would be identified without any possibility of error. And the skin implants would have to be put some place that would be convenient to the skin; for example your right hand or your forehead.
NEW DIFFICULT TO DIAGNOSE AND UNTREATABLE DISEASES
Next heading to talk about is Health and Disease. He said there would be new diseases to appear which had not ever been seen before. Would be very difficult to diagnose and be untreatable - at least for along time. No elaboration was made on this, but I remember, not long after hearing this presentation, when I had a puzzling diagnosis to make, I would be wondering, "is this was what he was talking about? Is this a case of what he was talking about?" Some years later, as AIDS ultimately developed, I think AIDS was at least one example of what he was talking about. I now think that AIDS probably was a manufactured disease.
SUPPRESSING CANCER CURES AS A MEANS OF POPULATION CONTROL
Cancer. He said. "We can cure almost every cancer right now. Information is on file in the Rockefeller Institute, if it's ever decided that it should be released. But consider - if people stop dying of cancer, how rapidly we would become overpopulated. You may as well die of cancer as something else."
Efforts at cancer treatment would be geared more toward comfort than toward cure. There was some statement that ultimately the cancer cures which were being hidden in the Rockefeller Institute would come to light because independent researchers might bring them out, despite these efforts to suppress them. But at least for the time being, letting people die of cancer was a good thing to do because it would slow down the problem of overpopulation.
Chapter Five: Your Narrator is Broken. Don’t Read this Section.
I keep thinking about the Magic Merck Sauce.
I like to go to the animal studies as I find them less carefully parsed to please the funders.
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2885.2008.01007.x
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Journal of Veterinary Pharmacology and Therapeutics
Free Access
Brain penetration of ivermectin and selamectin in mdr1a,b P-glycoprotein- and bcrp- deficient knockout mice
Abstract
P-glycoprotein, which is encoded by the multi-drug resistance gene (MDR1), highly restricts the entry of ivermectin into the brain by an ATP-driven efflux mechanism at the blood–brain barrier. In dogs with a homozygous MDR1 mutation though, ivermectin accumulates in the brain and provokes severe signs of neurotoxicosis and even death. In contrast to ivermectin, selamectin is safer in the treatment of MDR1 mutant dogs, suggesting that selamectin is transported differently by P-glycoprotein across the blood–brain barrier.
To test this, we applied selamectin to mdr1-deficient mdr1a,b−/− knockout mice and wild-type mice. Brain penetration, organ distribution, and plasma kinetics were analyzed after intravenous, oral, and dermal spot-on application in comparison with ivermectin. We found that in vivo both macrocyclic lactone compounds are substrates of P-glycoprotein and that these strongly accumulate in the brain of mdr1a,b−/− knockout mice compared with wild-type mice at therapeutic doses of 12 mg/kg selamectin and 0.2 mg/kg ivermectin. However, selamectin accumulates to a much lesser degree (5–10 times) than ivermectin (36–60 times) in the absence of P-glycoprotein.
This could explain the broader margin of safety of selamectin in MDR1 mutant dogs. In liver, kidney, and testes, ivermectin and selamectin accumulated less than four times as much in mdr1a,b mutant mice as in wild-type mice. Breast cancer resistance protein (Bcrp)-deficient bcrp−/− knockout mice were also included in the application studies, but showed no differences in brain concentrations or organ distribution of either ivermectin or selamectin compared with wild-type mice. This indicates that Bcrp is not a relevant efflux carrier for these macrocyclic lactone compounds in vivo at the blood–brain barrier.
PGlycoprotein is efflux (flush) mechanism to protect the blood brain barrier.
There are countless studies on IVM and Cancer.
It appears that the rationale of the cancer research is to stop "Multi-drug resistance" that *P-Glycoprotein provides. That resistance appears to be simply...the immune system is blocking outside agents, aka, “medicine” or…poison.
Ivermectin is the antiparasitic that has been New Coke crammed into your Brain Vector based on Proxy Logics of politics and so forth are currently marketed to hooomannnzzzz who don’t want Peter Mac’s brighter mRNA or siRNA or RFUCKINGANYNA in their fucking bodies but would very much like to chug pesticides as a prophylactic which is dangerously close to the logic of a VACCINE.
When you arrive at the conclusion that a “virus” was created from a computer sequence, and then “eliminated” in a vat of monkey kidney cells and fetal calf serum, now one MUST ASK WHY A CANCER TEAM WAS RUSHING TO SHOW THAT IVERMECTIN WAS AN ANTIVIRAL AS THE PANDEMIC WAS PEAKING! SO FAST!
Ivermectin. No way and I mean NO WAY is this mass push to get in critters an accident.
When I think like a Scorpion, "applications" emerge like bat to pangolin fake viruses.
For example.
Ostensible: To keep the chemotherapy (murder) drugs in the body longer.
Real: To keep the chemotherapy (murder) drugs in the body longer.
Chapter Six: Continue Not Reading a Non-STEM try to Analyze STEM Fuckery
Here is your first task, Detectives.
Right now.
Go seek out the Ivermectin dosing by body weight for your doggos for the prevention of parasites.
Compare it to the dosing of humans (mg/kg).
If you have a 100-lb. human, and a 100-lb. dog…what will be their dose of the prophylactic Ivermectin?
Look at prophylactic and at treatment doses for both parasites and viruses.
Compare them.
Make a chart.
Draw a graph.
There will be a distinction.
It will be in some cases, a penny to a dollar type distinction.
.0015 - .003 mg per pound of body weight for prophylaxis. (for parasites).
100-lb. dog = .15 to .30 mg.
Now go to Hoomanz for Antiviral prophylaxis.
And I am now trying to sort out how Pierre and the Boyzzz showed us the science of how IVM is a prophylactic for viruses. His papers were shot back due to conflict of interests, some of them.
Dose to Bodyweight of the Magic Merck Sauce.
Tricky because Pierre and Co. are using mg/kg body weight, so we have to translate to lbs. first.
.2mg/kg is the recommendation.
100-lb. hoooman weighs 45.36 kg.
Dose = 9.072 mg of Magic Merck Sauce.
100-lb. Dog: .15 to .30 mg.
100-lb. Hooman: 9.072 mg.
Doggie dose is .0165 to .033 of Hooman dose.
Gosh, why such a tiny dose when body weight is identical?
For the prophylactic effects of the Merck Sauce.
Are doggos and hooomanz really so different?
P-Glycoprotein genetic mutation in dogs.
Now start there.
Many many cancer studies with IVM. Going way back before the purported novel virus attack of 2020.
The IVM Good Team that got WAY WAY OUT IN FRONT of the novel coronavirus, *isolating* it and then immediately dropping that computer sequence shit into a cell culture and “found” that IVM killed New Mean Virus that conveniently was ravaging NYC…for eleven weeks…allegedly.
Find out what else they are looking into.
Histone-mediated transduction as an efficient means for gene delivery
·
APR 16
DARPA Steve Executive Summary:
By April, 2020, the IVM Good for NOVEL SUPERVIRUS is already all Scienced.
They want to put machine parasites in your intestines.
The End.
Thanks for reminding us all again of those nasty little star shaped 'mechanical parasites!' I'd almost managed to forget about them. When they first surfaced, there were questions raised about whether they were being 'added' to the swabs being used for pcr tests (up into the nasal cavity next to the brain).
And the analysis that so many of the efforts are just ways to get around the body's natural defenses is also an important reminder as each of us must do our own due diligence about what we will allow into our own bodies and bodies of children and other dependent family members. The time for trust is waaaay past.... ~ Ginger Breggin
I recall seeing “Theragrippers” a few years back and giving an involuntary shudder.
As others noted, this is right up Bob Langer’s street. Anything to do with delivery technologies, his lab will almost certainly have involvement.
One of my early consulting clients also used Bob Langer, because it was essentially a biotech with a formulation play.